Obesity Paradox and the Effect of NT-proBNP on All-Cause and Cause-Specific Mortality.

ABSTRACT:

Background

In heart failure patients, obesity is associated with better outcomes as compared to normal weight, a phenomenon called the obesity paradox.

Objective

To examine if obesity modifies the relationship between NT-proBNP and all-cause and cause-specific mortality in adults without coronary artery disease or heart failure history.

Methods

We used the National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2004 and linked it with mortality through December 31, 2019. Participants > 18 years were categorized into normal weight (BMI ≤ 25 kg/m²), overweight (BMI > 25-29.9 kg/m²) and obese (BMI > 29.9 kg/m²). NT-proBNP levels were categorized as low (< 126 pg/mL) or high (≥ 126 pg/mL). Using Cox proportional hazard

SUBMITTER: Bahniwal RK 

PROVIDER: S-EPMC11546245 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature