Visible-Light-Induced Singlet Oxygen-Promoted Arylation and Alkylation of Quinoxalin-2(1H)-ones and Quinolines.

ABSTRACT: We report a green and efficient visible-light-driven method for the arylation and alkylation of quinoxalin-2(1H)-ones and quinolines. This catalyst-free process utilizes air as the oxidant, offering mild reaction conditions, environmental sustainability, and broad functional group compatibility. The approach enables the synthesis of aryl and alkyl derivatives of quinoxalin-2(1H)-ones and quinolines with high to excellent yields.

SUBMITTER: Tan R 

PROVIDER: S-EPMC11547374 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature