Palladium-Catalyzed C-H Functionalization and Flame-Retardant Properties of Isophosphinolines.

ABSTRACT: C-H activation is a powerful strategy for forming C-C bonds without the need for prefunctionalization. In this paper, we present a general, direct, and regioselective palladium-catalyzed functionalization of a phosphorus heterocycle, 2-phenyl-1H-isophosphinoline 2-oxide. The mild reaction conditions enabled the introduction of various functionalized alkenes. Moreover, the flame-retardant properties of selected products clearly highlighted the synergy between the phosphine oxide and another heteroatom-based group, even in the condensed phase.

SUBMITTER: Mengue Me Ndong KP 

PROVIDER: S-EPMC11547386 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature