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Clinical features and prognostic factors of IV combined small cell lung cancer: A propensity score matching analysis.


ABSTRACT:

Background

Nowadays, the characteristics and treatment of combined small-cell lung carcinoma (CSCLC) remain controversial. This study aimed to analyze the features of clinical demographics, survival outcomes and treatment modalities among IV CSCLC, IV SCLC and IV NSCLC, to provide more evidence for the study of IV CSCLC.

Methods

All CSCLC, SCLC and NSCLC patient data were obtained from the SEER database (2010-2020). Pearson's χ2 test was used to compare the differences in clinical characteristics. Propensity score matching (PSM) was utilized to balance the bias of the variables between patients. Univariate and multivariate Cox proportional hazards regression analyses were performed to identify prognostic factors. KM analysis was used to calculate survival. Adjusted analyses

SUBMITTER: Cai S 

PROVIDER: S-EPMC11548789 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature