CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics data.

ABSTRACT:

Background

With advancements in sequencing and mass spectrometry technologies, multiomics data can now be easily acquired for understanding complex biological systems. Nevertheless, substantial challenges remain in determining the association between gene-metabolite pairs due to the nonlinear and multifactorial interactions within cellular networks. The complexity arises from the interplay of multiple genes and metabolites, often involving feedback loops and time-dependent regulatory mechanisms that are not easily captured by traditional analysis methods.

Findings

Here, we introduce Compounds And Transcripts Bridge (abbreviated as CAT Bridge, available at https://catbridge.work), a free user-friendly platform for longitudinal multiomics analysis to efficiently identify trans

SUBMITTER: Yang B 

PROVIDER: S-EPMC11548955 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature