Liver stiffness measurement predicts clinical outcomes in autoimmune hepatitis.

ABSTRACT:

Background & aims

Liver stiffness measurement (LSM) has been shown to adequately predict outcomes in patients with liver disease. However, the value of LSM as a predictor of disease progression in autoimmune hepatitis (AIH) remains to be determined. This study aimed to evaluate the role of LSM as a predictor of disease progression and decompensation of cirrhosis in patients with AIH.

Methods

This multicentre cohort study included 439 patients with histologically confirmed AIH and at least one LSM during follow-up. The association between the first LSM performed at least 6 months after treatment initiation (baseline LSM [BLSM]) and cirrhosis development and poor outcomes (decompensation, liver transplantation, and/or liver-related death) was assessed using Cox regression and

SUBMITTER: Olivas I 

PROVIDER: S-EPMC11550196 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature