Aberrant dynamic functional network connectivity in patients with diffuse axonal injury.

ABSTRACT: Diffuse axonal injury (DAI) results in aberrant functional connectivity and is significantly linked to cognitive impairment. Nevertheless, the network mechanisms influencing neurocognitive function following DAI remain unclear. This study aimed to examine the characteristics of static and dynamic functional network connectivity (FNC) in patients with DAI. Resting-state functional magnetic resonance imaging data were collected from 26 patients with DAI and 27 healthy controls. Resting-state networks were extracted using independent component analysis. We evaluated the connectivity strength through spatial maps and static FNC, and then further dynamic properties were identified using a sliding time-window approach and k-means clustering, and investigated their associations with clinical vari

SUBMITTER: Li J 

PROVIDER: S-EPMC11550476 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature