Association between RANTES/CCL5 levels with Plasmodium infections and malaria severity: a systematic review.

ABSTRACT:

Background

Malaria continues to be a significant global health concern, and developing effective therapeutic strategies requires an understanding of the immune response to the disease. This systematic review synthesized the current body of research on the role of regulated on activation, normal T cell expressed and secreted (RANTES)-in the pathogenesis and disease severity of malaria.

Methods

A systematic review protocol was registered with PROSPERO under the registration number CRD42024535822. The systematic review was conducted following PRISMA guidelines to identify studies examining RANTES levels in individuals infected with Plasmodium species. Searches were performed across multiple databases, including ProQuest, Journals@Ovid, Embase, Scopus, PubMed, and MEDLINE. Furth

SUBMITTER: Kwankaew P 

PROVIDER: S-EPMC11550525 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature