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Exploring the protective effect of silver <i>Croton tiglium</i> nano-extract against azoxymethane induced toxicity in female reproductive organs in rats.


ABSTRACT: Reproductive toxicity from food and environmental contaminants has greatly affected human life. Plants are a fundamental source of bioactive components for relieving the harmful effects of pollutants. Hydrazine metabolites pose health threats when they enter the food chain. Croton tiglium (C. tiglium) exhibits anti-inflammatory and anti-tumor properties. Silver nanoparticles enhance the chemical stability of C. tiglium. Reproductive toxicity of Azoxymethane (AOM) and anticancer effects of silver C. tiglium were evaluated. Thirty-six adult female rats were divided into six groups (n = 6) and treated with AOM with or without silver C. tiglium nano-extract as pre- and post-treatment. Sexual hormones and proteins were assessed under silver C. tigliu

SUBMITTER: Aboulthana WM 

PROVIDER: S-EPMC11550675 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature