Investigating the role of thrombosis and false lumen orbital orientation in the hemodynamics of Type B aortic dissection.

ABSTRACT: While much about the fundamental mechanisms behind the initiation and progression of Type B aortic dissection (TBAD) is still unknown, predictive models based on patient-specific fluid-structure interaction (FSI) simulations can help in risk stratification and optimal clinical decision-making. Aiming at the development of personalized treatment, FSI models can be leveraged to investigate the interplay between complex aortic flow patterns and anatomical features, while considering the deformation of the arterial wall and the dissection flap. In this study, the hemodynamics of false lumen thrombosis, a large fenestration, and the orbital orientation of the false lumen is studied through image-based FSI simulations on three TBAD patient-specific geometries. A new pipeline is developed leverag

SUBMITTER: Messou JCE 

PROVIDER: S-EPMC11550845 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature