Angiopoietin-2 as a prognostic biomarker in septic adult patients: a systemic review and meta-analysis.

ABSTRACT:

Background

The impairment of endothelial function represents a key pathophysiological mechanism in the development of sepsis. This research aimed to evaluate the prognostic significance of angiopoietin-2 (Ang-2), an endothelial biomarker, in predicting mortality in sepsis patients.

Methods

Chinese and English studies were systematically retrieved in PubMed, Cochrane Library, Embase, WanFang, CNKI, CQVIP, and CBM databases up to July 16, 2023. We conducted a study selection established upon predefined inclusion and exclusion criteria and used the Newcastle-Ottawa scale (NOS) to assess its quality. We extracted available data from the included studies for data analysis.

Results

The final inclusion comprised 33 studies with 4703 participants. According to the NOS, one st

SUBMITTER: Zhuo M 

PROVIDER: S-EPMC11551087 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature