Diuretics and mortality reduction in incident dialysis patients: a two-year observational study.

ABSTRACT: Fluid overload predicts morbidity and mortality in dialysis patients. Diuretics can reduce fluid overload, but their effects on morbi-mortality following inception remain ill-defined. To determine whether diuretics reduce mortality and hospitalization rates in incident dialysis patients in the first 2 years after inception. Adult patients starting dialysis between 2009 and 2015 in the REIN registry were matched with the SNDS database and divided into four subgroups according to loop diuretics exposure: < 5%, 5-50%, 50-80% or > 80% over the observation period of each patient. The incidence of hospitalization was described based on the primary diagnoses of the discharge summaries and codes. In this study, which included 67,736 patients, 53,829 (79.5%) who had varying degrees of diuretic expo

SUBMITTER: Ingwiller M 

PROVIDER: S-EPMC11551180 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature