Atrial fibrillation substrate and impaired left atrial function: a cardiac MRI study.

ABSTRACT:

Aims

Structural and fibrotic remodelling is a well-known contributor to the atrial fibrillation (AF) substrate. Epicardial adipose tissue (EAT) is increasingly recognized as a contributor through electrical remodelling in the atria. We aimed to assess the association of LA fibrosis and EAT with LA strain and function using cardiac magnetic resonance (CMR) imaging in patients with AF.

Methods and results

LA fibrosis was assessed using late gadolinium enhancement CMR, LA EAT was assessed using the fat-water separation Dixon sequence, and feature tracking was applied to assess global longitudinal strain in its three components [reservoir (GLRS), conduit (GLCdS), and contractile (GLCtS)]. LA emptying fraction and LA volume were measured using the cine sequences. All CMR images w

SUBMITTER: Chahine Y 

PROVIDER: S-EPMC11551228 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature