Is autologous platelet-rich plasma capable of increasing hair density in patients with androgenic alopecia? A systematic review and meta-analysis of randomized clinical trials.

ABSTRACT:

Fundamentals

Platelet-rich plasma (PRP) has been progressively more used in androgenetic alopecia (AGA).

Objectives

The authors aimed to evaluate PRP efficacy compared to placebo in AGA.

Methods

A comprehensive search was conducted across seven databases, until 01/04/2023. Randomized clinical trials focusing on AGA and PRP use to increase hair density were included. Patients aged between 15 and 63 years, diagnosed with AGA characterized by Norwood I‒VII and Ludwig I‒III scales, were included. Studies with a sample size <10, lacking PRP processing method, focusing on complementary therapies or other alopecias, were excluded. The authors conducted subgroup analysis for activator, spin method, study design, risk of bias, and gender. Meta-regression was conducted for acti

SUBMITTER: Kieling L 

PROVIDER: S-EPMC11551241 | biostudies-literature | 2024 Nov-Dec

REPOSITORIES: biostudies-literature