Assessing the feasibility of using toenails as biomarkers for estimating inorganic arsenic exposure in Japanese adults.

ABSTRACT:

Background

Long-term exposure to inorganic arsenic (InAs) through arsenic (As)-contaminated drinking water poses serious health risks. However, epidemiological studies focusing on low-level dietary exposure to InAs are lacking. Furthermore, although toenail clippings are used as biomarkers for assessing As exposure in areas with contaminated drinking water, to date, no method has been developed for using toenails as a biomarker of long-term InAs exposure in individuals with lower exposure levels, e.g., from dietary sources including fish and seaweeds. Therefore, this study aimed to assess the feasibility of using toenails as biomarkers for estimating InAs exposure in Japanese adults.

Methods

Three sets of 7-day diet records and toenail clipping samples were collected from 39

SUBMITTER: Oguri T 

PROVIDER: S-EPMC11551441 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature