Ten-year follow-up of age-related macular degeneration in the age-related eye disease study: AREDS report no. 36.

ABSTRACT:

Importance

Providing long-term follow-up of the natural history of age-related macular degeneration (AMD) and associated risk factors will facilitate future epidemiologic studies and clinical trials.

Objective

To describe 10-year progression rates to intermediate or advanced AMD.

Design, setting, and participants

We observed the Age-Related Eye Disease Study (AREDS) participants for an additional 5 years after a randomized clinical trial of antioxidant vitamins and minerals was completed. Observation occurred at 11 clinical sites of medical retinal practices from academic institutions and community medical centers. Participants aged 55 to 80 years with no AMD or AMD of varying severity (n = 4757) were followed up in the AREDS trial for a median duration of 6.5 years.

SUBMITTER: Chew EY 

PROVIDER: S-EPMC11551520 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature