Associations of maternal serum ferritin levels across gestation with gestational diabetes mellitus: A longitudinal cohort study.

ABSTRACT:

Background

The longitudinal changes in maternal serum ferritin (SF) levels across gestation, which indirectly reflect iron supplementation, have not been extensively investigated in relation to gestational diabetes mellitus (GDM).

Methods

We conducted a retrospective cohort study at a tertiary maternal hospital in Shanghai. Women with SF concentration measurements at 8.0-13.6 weeks' gestation (GW), 29.0-31.6 GW, and an oral glucose tolerance test (OGTT) at 24-28 GW were included. We utilized logistic regression analysis to assess GDM association with maternal SF levels and longitudinal changes.

Results

The study included 17 560 women, with 2160 (12.3%) participants diagnosed with GDM. Adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for GDM across increasin

SUBMITTER: Mo H 

PROVIDER: S-EPMC11551590 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature