Functionalized Nanodiamonds for Targeted Neuronal Electromagnetic Signal Detection.

ABSTRACT: Intracellular sensing technologies necessitate a delicate balance of spatial resolution, sensitivity, biocompatibility, and stability. While existing methods partially fulfill these criteria, none offer a comprehensive solution. Nanodiamonds (NDs) harboring nitrogen-vacancy (NV) centers have emerged as promising candidates due to their sensing capabilities under biological conditions and their ability to meet all aforementioned requirements. This study focuses on expanding the application of NDs and NV center-based sensing to neuronal contexts by investigating their functionalization and subsequent effects on three distinct cell lines relevant to neurodegenerative disease research. Our study concentrates on positioning fluorescent NDs (FNDs) with NV center point defects onto neuronal cell

SUBMITTER: Costa BNL 

PROVIDER: S-EPMC11551900 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature