Prospective Preference Assessment for the Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN (PEACE-PAIN) Trial.

ABSTRACT:

Background

Negative perceptions of psilocybin and challenges of participant enrollment may represent barriers to conducting a randomized controlled trial examining psilocybin for chronic neuropathic pain.

Aim

Prior to trial initiation, we aimed to examine patient attitudes toward the trial via a prospective preference assessment.

Methods

Twenty-six patients with chronic neuropathic pain participated in a prospective preference assessment comprising quantitative (survey) and qualitative (interview) components. Content analysis was used to inductively and deductively identify factors that would motivate or discourage participation in the proposed trial. Demographics, clinical characteristics, and perceptions of psilocybin were collected to explore differences in charact

SUBMITTER: Lee J 

PROVIDER: S-EPMC11552286 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature