EV-miRNA associated with environmental air pollution exposures in the MADRES cohort.

ABSTRACT: Air pollution is a hazardous contaminant, exposure to which has substantial consequences for health during critical periods, such as pregnancy. MicroRNA (miRNA) is an epigenetic mechanism that modulates transcriptome responses to the environment and has been found to change in reaction to air pollution exposure. The data are limited regarding extracellular-vesicle (EV) miRNA variation associated with air pollution exposure during pregnancy and in susceptible populations who may be disproportionately exposed. This study aimed to identify EV-miRNA expression associated with ambient, residential exposure to PM_2.5, PM₁₀, NO₂, O₃ and with traffic-related NO_x in 461 participants of the MADRES cohort, a low income, predominantly Hispanic preg

SUBMITTER: Foley HB 

PROVIDER: S-EPMC11552520 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature