Factors Associated With Missing Biological Samples in the Dog Ageing Project.

ABSTRACT:

Background

The Dog Aging Project (DAP) is a longitudinal study examining aging in US companion dogs, where missing data pose a challenge to result validity and statistical power. Early recognition and procedural adjustments are vital to address missing samples.

Objectives

This research assesses missing biospecimen samples within the PRECISION cohort of the DAP, aiming to identify contributing factors and propose mitigation strategies.

Methods

Ninety sample kits collected between August 2021 and October 2021 were evaluated for the missingness of individual kit components. A primary assessment reviewed the missingness of each sample type with hypothesized associated factors. A secondary assessment addressed the missingness of plasma and serum aliquots made after check-i

SUBMITTER: Holland SN 

PROVIDER: S-EPMC11554544 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature