Pharmacological and non-pharmacological treatments in amyotrophic lateral sclerosis: an Italian real-world data study.

ABSTRACT:

Background and purpose

The purpose was to describe the use patterns of pharmacological and non-pharmacological therapies and investigate potential determinants of riluzole use in patients newly diagnosed with amyotrophic lateral sclerosis (ALS) in three Italian regions.

Methods

Amyotrophic lateral sclerosis patients were selected from administrative healthcare databases of Latium, Tuscany and Umbria from 1 January 2014 to 31 December 2019 based on hospital- and disease-specific co-payment exemption data. The first trace of ALS was considered the index date. Incident ALS cases were those without a trace of ALS during the 3-year look back. Patients were described in terms of demographics, clinical characteristics and drug use at baseline, and were classified into four categori

SUBMITTER: Paoletti O 

PROVIDER: S-EPMC11554872 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature