Association of dementia with impaired kidney function and plasma biomarkers: A population-based study.

ABSTRACT:

Background and purpose

Emerging evidence has linked impaired kidney function with dementia in older adults, but the neuropathological pathways underlying their association remain poorly understood. We sought to examine the relationships of kidney function with dementia and plasma biomarkers in a Chinese rural population.

Methods

This population-based study used data from the baseline examination of the Multimodal Interventions to Delay Dementia and Disability in rural China (MIND-China) cohort (March-September 2018; n = 5715). Kidney function was assessed using estimated glomerular filtration rate (eGFR) based on serum creatinine level. Dementia, Alzheimer's disease (AD) and vascular dementia (VaD) were diagnosed according to the international criteria. Plasma biomarkers wer

SUBMITTER: Wang N 

PROVIDER: S-EPMC11555029 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature