Pelvic autonomic dysfunction is common in patients with pure autonomic failure.

ABSTRACT:

Background and purpose

Pure autonomic failure (PAF) presents primarily as cardiovascular autonomic failure and may phenoconvert to other neurodegenerative disorders. However, the involvement of other autonomic functions has been poorly evaluated. This study aims to characterize genitourinary and bowel dysfunction and explore their relationship with cardiovascular autonomic dysfunction.

Methods

Pure autonomic failure patients underwent cardiovascular autonomic testing and an assessment of pelvic autonomic dysfunction using urinary, sexual symptoms questionnaires and a bladder diary. Demographic, clinical features and related medical comorbidities were assessed.

Results

Twenty-five patients (10 males) with PAF were included (mean age 71 ± 8 years; disease duration 13 ± 

SUBMITTER: Vichayanrat E 

PROVIDER: S-EPMC11555151 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature