Molecular characteristics of atopic dermatitis patients with clinical remission.

ABSTRACT:

Introduction

Atopic dermatitis (AD) is a frequent disease in infants with diverse clinical evolution. Although multiple studies have assessed inflammatory changes in chronic AD, little is known about the molecular transition from symptomatic stage to clinical remission without pharmacotherapy.

Objective

The aim of the study was to evaluate clinical and inflammatory factors and its relationship with AD clinical evolution.

Methods

Three groups of participants older than 10 years of age were recruited; 2 AD groups and 1 non-AD group. The AD-remission group (more than 1 year without AD symptoms and without pharmacotherapy), the AD-persistent group (AD symptoms and pharmacotherapy), and 1 non-AD group. We measured eosinophil peroxidase (EPX), eosinophil cationic protein (E

SUBMITTER: Sanchez A 

PROVIDER: S-EPMC11555337 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature