Phenotyping Kidney Function in Young Adults With High Blood Pressure: The African-PREDICT Study.

ABSTRACT: Biomarkers of kidney function, including glomerular, tubular, and fibrotic markers, have been associated with blood pressure in elderly populations and individuals with kidney and cardiovascular diseases. However, limited information is available in young adults. In this study, we compared levels of several kidney function biomarkers between normotensive and hypertensive young adults and explored the associations of these biomarkers with blood pressure within these groups. In this cross-sectional assessment, twenty-four-hour (24-h) blood pressure measurements of 1055 participants (mean age = 24.6 years) were used to classify hypertension as per the 2018 ESC/ESH guidelines. Biomarkers of kidney function included estimated glomerular filtration rate, urinary albumin, alpha-1 microglobulin (u

SUBMITTER: Degenaar A 

PROVIDER: S-EPMC11555542 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature