Meta-analysis of gonadal transcriptome provides novel insights into sex change mechanism across protogynous fishes.

ABSTRACT: Protogyny, being capable of changing from female to male during their lifetime, is prevalent in 20 families of teleosts but is believed to have evolved within specific evolutionary lineages. Therefore, shared regulatory factors governing the sex change process are expected to be conserved across protogynous fishes. However, a comprehensive understanding of this mechanism remains elusive. To identify these factors, we conducted a meta-analysis using gonadal transcriptome data from seven species. We curated data pairs of ovarian tissue and transitional gonad, and employed ratios of expression level as a unified criterion for differential expression, enabling a meta-analysis across species. Our approach revealed that classical sex change-related genes exhibited differential expression levels

SUBMITTER: Nozu R 

PROVIDER: S-EPMC11555629 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature