Impact of sociodemographic disparities on sarcopenia, telomere length, and mortality in patients with liver disease in the US population.

ABSTRACT:

Background & aims

Sarcopenia is common in patients with liver disease and both sarcopenia and short telomeres are associated with mortality, however their relationship in patients with liver disease remains unknown.

Methods

A cohort of 16,072 adults from the National Health and Nutrition Examination Survey from 1999 to 2006 was analyzed. Liver disease was defined by aminotransferases and classified into etiology-based categories. Sarcopenia was defined by dual-energy x-ray absorptiometry. All analyses were conducted separately on each multiple imputation data set and combined via Rubin's rules. P-values for group comparisons were calculated by testing logistic regression parameter estimates. Cox proportional hazards regression was used for mortality analysis with mortality d

SUBMITTER: Kezer CA 

PROVIDER: S-EPMC11555844 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature