Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice.

ABSTRACT: Witmer et al. provide genomic and molecular evidence to demonstrate that Fndc5 (irisin myokine precursor protein) is translated in humans from an overlooked upstream ATG codon.

SUBMITTER: Witmer NH 

PROVIDER: S-EPMC11555857 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature