The outcomes of children with primary malignant renal tumors: a 14-year single-center experience.

ABSTRACT:

Background

Wilms tumor (WT) is the most common malignant renal tumor in children. This study investigated the clinical features, pathological findings, and outcomes of children with malignant renal tumors in Southern Iran. Factors associated with recurrence and mortality were assessed.

Methods

Electronic files of children with malignant renal tumors from 2009 to 2023 were reviewed. The 5-year overall survival (OS) and event-free survival (EFS) were reported.

Results

Eighty-three patients (44 males) with a median age of 40 months (range: 3-122) were included. WT was the most common pathological variant (94%). Anaplasia was found in 17.3% of patients. Upfront chemotherapy followed by nephrectomy was performed in 54.2% of the patients. Ten patients (12%) experienced rela

SUBMITTER: Bordbar S 

PROVIDER: S-EPMC11555868 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature