Gender differences in clinical characteristics and influencing factors of suicide attempts in first-episode and drug-naive major depressive disorder patients with comorbid metabolic syndrome.

ABSTRACT:

Backgrounds

Patients with major depressive disorder (MDD) have a high rate of metabolic syndrome (MetS), which could worsen disease progression. One of the most serious progressions in MDD is suicide attempts (SAs). Previous studies have found gender differences in MetS and SAs among MDD patients respectively. Therefore, we aimed to explore gender differences of SAs in first-episode and drug-naïve (FEDN) MDD patients with comorbid MetS.

Methods

1718 outpatients with FEDN MDD were recruited. Depression, anxiety and psychotic symptoms were evaluated using the Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA) and Positive and Negative Syndrome Scale (PANSS) positive subscale, respectively. Blood sugar, blood fat, blood pressure and body mass index (BMI) were measu

SUBMITTER: Sun P 

PROVIDER: S-EPMC11555937 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature