Prevalence of comorbid autoimmune diseases and antibodies in newly diagnosed multiple sclerosis patients.

ABSTRACT:

Background

Diagnosing multiple sclerosis (MS) is challenging due to diverse symptoms and the absence of specific biomarkers. Concurrent autoimmune diseases (AID) or non-specific antibodies further complicate diagnosis, progression monitoring, and management. Data on AID prevalence in MS patients are sparse. This study aims to identify concurrent AIDs alongside MS.

Methods

In this retrospective single-center study, we analyzed patient records at our university hospital from 2010 to 2017, focusing on cases suspected of inflammatory demyelinating disease. The 2017 McDonald criteria were applied. Additionally, we measured neurofilament light (NfL) levels from available CSF samples in our biobank.

Results

We identified a total of 315 patients, of whom 66% were women. In to

SUBMITTER: Jendretzky KF 

PROVIDER: S-EPMC11556020 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature