Photoreceptor Characteristics in Diabetic Retinopathy vs Controls Using Adaptive Optics Imaging: Systematic Review.

ABSTRACT: Purpose: To assess the differences in morphological photoreceptor outcomes measured using adaptive optics (AO)-assisted imaging between individuals with diabetes or prediabetes and healthy controls. Methods: A systematic search was conducted across MEDLINE, Embase, and Cochrane databases from January 2000 to June 2023. Studies that used AO-assisted imaging modalities to quantitatively compare photoreceptor outcomes in patients with diabetes or prediabetes with healthy controls were included. Results: Eleven studies consisting of 551 eyes were included. Most studies reported significant differences in photoreceptor outcomes between diabetic and healthy populations, particularly as diabetic retinopathy (DR) severity increased. Cone regularity was the most sensitive param

SUBMITTER: Grad J 

PROVIDER: S-EPMC11556365 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature