Predictors and clinical impact of worsening left ventricular ejection fraction after mitral transcatheter edge-to-edge repair.

ABSTRACT:

Background

Little is known about the effects of left ventricular ejection fraction (LVEF) worsening after transcatheter edge-to-edge valve repair (TEER) for mitral regurgitation (MR).

Aims

This study investigated the predictors and clinical impact of LVEF worsening after TEER for primary MR (PMR) and secondary MR (SMR).

Methods

This study included 2,019 patients (493 with PMR and 1,526 with SMR) undergoing successful TEER (postprocedural MR grade ≤2+) in the OCEAN-Mitral registry. The patients were categorised into worsened LVEF (wEF), defined as a relative decrease of >12.9% in LVEF at discharge, and preserved LVEF (pEF). The serial changes in left ventricular (LV) function at 1 year were also evaluated.

Results

Following TEER, 657 (32%) patients demonstrated

SUBMITTER: Ono S 

PROVIDER: S-EPMC11556402 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature