A genomic analysis reveals the diversity of cellulosome displaying bacteria.

ABSTRACT:

Introduction

Several species of cellulolytic bacteria display cellulosomes, massive multi-cellulase containing complexes that degrade lignocellulosic plant biomass (LCB). A greater understanding of cellulosome structure and enzyme content could facilitate the development of new microbial-based methods to produce renewable chemicals and materials.

Methods

To identify novel cellulosome-displaying microbes we searched 305,693 sequenced bacterial genomes for genes encoding cellulosome proteins; dockerin-fused glycohydrolases (DocGHs) and cohesin domain containing scaffoldins.

Results and discussion

This analysis identified 33 bacterial species with the genomic capacity to produce cellulosomes, including 10 species not previously reported to produce these complexes, such a

SUBMITTER: Minor CM 

PROVIDER: S-EPMC11557425 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature