Exploring the impact of polychlorinated biphenyls on comorbidity and potential mitigation strategies.

ABSTRACT:

Introduction

Polychlorinated Biphenyls (PCBs) persist in the environment and accumulate in humans. Currently, there is a lack of understanding about the overall impact of PCBs on human health, and effective interventions for exposed populations are insufficient.

Methods

Our study aimed to assess the impact of PCBs on various diseases and mortality risks using data from the National Health and Nutrition Examination Survey, while proposing lifestyle adjustments, particularly dietary modifications, to mitigate mortality risk. Statistical analyses employed principal component analysis, multifactorial logistic regression, multifactorial Cox regression, comorbidity network analysis, and machine learning prediction models.

Results

Results indicated significant associations b

SUBMITTER: Gao Y 

PROVIDER: S-EPMC11557481 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature