Task-switching mechanisms under methamphetamine cravings: sex differences in cued and voluntary task-switching.

ABSTRACT:

Introduction

This study explored the effects of task-switching type and sex on the task-switching ability of methamphetamine abstainers, as well as the differences in brain mechanisms under drug cravings under drug cravings using near-infrared spectroscopy.

Methods

Craving-inducing videos were used to arouse 20 methamphetamine abstainers (including 10 men), whose switching ability was then assessed using voluntary and cued task-switching exercises.

Results

During task-switching under methamphetamine cravings, the activation of the premotor cortex (PMC), supplementary motor area (SMA), frontal eye field (FEF), and dorsolateral prefrontal cortex (DLPFC) in women was significantly stronger than in men, while the activation of FEF in men was significantly stronger than in

SUBMITTER: Jiang H 

PROVIDER: S-EPMC11557557 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature