Synthetic hematocrit from virtual non-contrast images for myocardial extracellular volume evaluation with photon-counting detector CT.

ABSTRACT:

Objectives

To assess the accuracy of a synthetic hematocrit derived from virtual non-contrast (VNC) and virtual non-iodine images (VNI) for myocardial extracellular volume (ECV) computation with photon-counting detector computed tomography (PCD-CT).

Materials and methods

Consecutive patients undergoing PCD-CT including a coronary CT angiography (CCTA) and a late enhancement (LE) scan and having a blood hematocrit were retrospectively included. In the first 75 patients (derivation cohort), CCTA and LE scans were reconstructed as VNI at 60, 70, and 80 keV and as VNC with quantum iterative reconstruction (QIR) strengths 2, 3, and 4. Blood pool attenuation (BP_mean) was correlated to blood hematocrit. In the next 50 patients (validation cohort), synthetic hematocrit wa

SUBMITTER: Mergen V 

PROVIDER: S-EPMC11557661 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature