Disease severity prognostication in primary sclerosing cholangitis: a validation of the Anali scores and comparison with the potential functional stricture.

ABSTRACT:

Objectives

Our aim was twofold. First, to validate Anali scores with and without gadolinium (ANALI_Gd and ANALI_NoGd) in primary sclerosing cholangitis (PSC) patients. Second, to compare the ANALIs prognostic ability with the recently-proposed potential functional stricture (PFS).

Materials and methods

This retrospective study included 123 patients with a mean age of 41.5 years, who underwent gadoxetic acid-enahnced MRI (GA-MRI). Five readers independently evaluated all images for calculation of ANALI_Gd and ANALI_NoGd scores based upon following criteria: intrahepatic bile duct change severity, hepatic dysmorphia, liver parenchymal heterogeneity, and portal hypertension. In addition, hepatobiliary contrast excretion into first-order b

SUBMITTER: Poetter-Lang S 

PROVIDER: S-EPMC11557717 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature