Women may not benefit from repeated frozen embryo transfers: a retrospective analysis of the cumulative live birth rate of 43 972 women.

ABSTRACT:

Study question

Which specific groups of women would not benefit from repeated frozen embryo transfers (FETs)?

Summary answer

Women over 45 years of age should stop treatment after three FET attempts due to the absence of further benefits, while women aged 40-45 years and those with a diminished ovarian reserve and other causes of infertility have a lower chance of improving their cumulative live birth rate (CLBR) within five FET cycles and experience fewer advantages from repeated transfers.

What is known already

In real-life scenarios of ART, women who fail to achieve a live birth often choose to undergo repeated FETs via the freeze-all strategy.

Study design size duration

This retrospective study included 43 972 women who underwent 86 496 oocyte retrieval cyc

SUBMITTER: Zeng Y 

PROVIDER: S-EPMC11557905 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature