Safety reporting in trials on glaucoma interventions registered in ClinicalTrials.gov and corresponding publications.

ABSTRACT: Accurate, comprehensive, and consistent reporting of adverse events is of great importance for treatment decisions in clinical practice and patient safety. Aiming to evaluate the completeness and transparency of reported adverse events we conducted a retrospective analysis of completed clinical trials on glaucoma interventions registered in ClinicalTrials.gov from September 27, 2009, and updated and with results on or before November 1, 2023, as well as in corresponding journal publications. Any difference in completeness, number, or terminology/description of adverse events and all-cause mortality between ClinicalTrials.gov and the publication was categorized as inconsistent reporting of adverse events. All 79 trials with results both in the registry and a journal publication exhibited at

SUBMITTER: Kreso A 

PROVIDER: S-EPMC11557964 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature