Hemodynamic and clinical outcomes with balloon-expandable valves versus self-expanding valves in patients with small aortic annulus undergoing transcatheter aortic valve replacement: A <i>meta</i>-analysis of randomized controlled trials and propensity score matched studies.

ABSTRACT: Transcatheter aortic valve replacement (TAVR) is considered more effective than surgical aortic valve implantation for patients with a small aortic annulus (SAA), however, the comparative efficacy of different transcatheter heart valves (THVs) remains uncertain. A literature search was performed across databases from their inception until June 2024 to identify eligible randomized controlled trials (RCTs) and propensity-score matched (PSM) studies. Clinical outcomes were evaluated using a random-effects model to pool risk ratios (RRs) with 95 % confidence intervals (CIs). The analysis included 10 studies with 2,960 patients. BEVs were associated with a significantly smaller indexed effective orifice area (MD: -0.18, 95 % CI: -0.27 to -0.10), and a higher transvalvular mean pressure gradient

SUBMITTER: Ahmed M 

PROVIDER: S-EPMC11558639 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature