Exploring the sophistications of unexplained recurrent pregnancy loss: A case-control study.

ABSTRACT:

Background

Unexplained recurrent pregnancy loss (URPL) is a significant obstetric challenge affecting maternal health and well-being. Genetic factors, including mutations in the methylenetetrahydrofolate reductase (MTHFR) gene and elevated homocysteine levels, are increasingly recognized as contributors to URPL, though their precise roles remain complex. This study aimed to comprehensively explore these factors.

Objectives

This study examines the links between MTHFR gene polymorphisms (C677T and A1298C), plasma homocysteine levels, and URPL. It also aims to create a predictive model for URPL based on these factors.

Design

A case-control study with Vietnamese women who had at least one pregnancy between January 2017 and June 2020, recruited from Medlatec Hospital and H

SUBMITTER: Que TT 

PROVIDER: S-EPMC11558731 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature