The association of Helicobacter pylori with adverse pregnancy outcomes in three European birth cohorts.

ABSTRACT:

Background

Helicobacter pylori is a prevalent infection that may complicate pregnancy, but evidence remains limited, controversial and may not apply to all pregnant women.

Objective

This study aims to evaluate whether Helicobacter pylori is a risk factor for adverse pregnancy outcomes and to identify vulnerable subpopulations.

Study design

Multiplex serology was utilized to measure blood levels of immunoglobulin G against eight Helicobacter pylori antigens in 1372 pregnant women from three European birth cohorts: BiB (United Kingdom), Rhea (Greece) and INMA (Spain). Outcomes of interest included gestational diabetes mellitus, gestational hypertension, preeclampsia, preterm birth and small for gestational age neonates, as well as prenatal anxiety and depression. Adjust

SUBMITTER: Galan R 

PROVIDER: S-EPMC11558891 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature