Factors Influencing the Timing of Ovarian Tissue Cryopreservation in Young Girls.

ABSTRACT: The aim of this study was to identify pitfalls in ovarian tissue cryopreservation protocol from referral to surgical procedure and to analyze factors associated with chemotherapy exposure of the cryopreserved tissue and decreased ovarian function in a cohort of young girls at high risk of infertility. The study population comprised 200 girls eligible for ovarian tissue cryopreservation between 2002 and 2020 at the Children's Hospital of the University Central Hospital of Helsinki (Finland). Analyses included evaluation of the proportion of patients who underwent ovarian tissue cryopreservation, factors associated with patient selection and timing of ovarian tissue cryopreservation, and ovarian function during long-term follow-up in relation to oncological treatments. Lack of counselling wa

SUBMITTER: Pampanini V 

PROVIDER: S-EPMC11558924 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature