Metal mixture exposures and serum lipid levels in childhood: the Rhea mother-child cohort in Greece.

ABSTRACT:

Background

Growing evidence suggests that cardiovascular disease develops over the lifetime, often beginning in childhood. Metal exposures have been associated with cardiovascular disease and important risk factors, including dyslipidemia, but prior studies have largely focused on adult populations and single metal exposures.

Objective

To investigate the individual and joint impacts of multiple metal exposures on lipid levels during childhood.

Methods

This cross-sectional study included 291 4-year-old children from the Rhea Cohort Study in Heraklion, Greece. Seven metals (manganese, cobalt, selenium, molybdenum, cadmium, mercury, and lead) were measured in whole blood using inductively coupled plasma mass spectrometry. Serum lipid levels included total cholesterol, tr

SUBMITTER: Yim G 

PROVIDER: S-EPMC11559660 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature