Anti-epileptic Drugs Use and Increased Risk of Stroke: A Systematic Review.

ABSTRACT: Background: Antiepileptic drugs (AEDs), the predominant treatment for epilepsy, are also utilised for migraine, neuropathic pain, and bipolar disorders, accounting for 1% of usage among the common population. There is a greater risk of stroke, heart attack, and arrhythmia among AED users particularly those with enzyme-inducing properties. Summary: This systematic review aimed to look into the ischemic stroke risk among AED users, particularly in patients who had never had a cerebrovascular accident before. English-language literature was searched in the databases of PubMed, EMBASE, and Google Scholar between 2000 and 2021. Studies should report the association between AEDs and the ischemic stroke risk. The outcomes for assessing efficacy and safety were: event ratio, hazard r

SUBMITTER: Prasad Gajurel B 

PROVIDER: S-EPMC11559889 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature