Managing Major Peripheral Nerves in Forearm-Level Amputations With TMR and RPNI: What's the Best Recipe?

ABSTRACT:

Background

Targeted muscle reinnervation (TMR) and regenerative peripheral nerve interface (RPNI) prevent symptomatic neuroma formation in amputees. Forearm-level amputations present multiple muscular targets, making it challenging to determine the ideal treatment. The purpose of this study was to evaluate the best TMR targets, role of RPNI, and appropriate patient-selection criteria in forearm-level amputations. We hypothesized that deep and distal TMR targets would best prevent symptomatic neuromas, RPNI would prove a success adjunct, and patients with poorly controlled diabetes would not develop symptomatic neuromas regardless of nerve management.

Methods

We retrospectively identified forearm-level amputations performed between 2017 and 2022. Patients with TMR by outside

SUBMITTER: Rees AB 

PROVIDER: S-EPMC11559940 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature