Sex-specific prediction of cardiogenic shock after acute coronary syndromes: the SEX-SHOCK score.

ABSTRACT:

Background and aims

Cardiogenic shock (CS) remains the primary cause of in-hospital death after acute coronary syndromes (ACS), with its plateauing mortality rates approaching 50%. To test novel interventions, personalized risk prediction is essential. The ORBI (Observatoire Régional Breton sur l'Infarctus) score represents the first-of-its-kind risk score to predict in-hospital CS in ACS patients undergoing percutaneous coronary intervention (PCI). However, its sex-specific performance remains unknown, and refined risk prediction strategies are warranted.

Methods

This multinational study included a total of 53 537 ACS patients without CS on admission undergoing PCI. Following sex-specific evaluation of ORBI, regression and machine-learning models were used for variable sele

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11560280 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature