Insights into the historical trajectory and research trends of immune checkpoint blockade in colorectal cancer: visualization and bibliometric analysis.

ABSTRACT:

Background

Colorectal cancer (CRC) is a malignant tumor that poses a significant threat to human health due to rising incidence and mortality rates. In recent years, immune checkpoint blockade (ICB) therapy, represented by Programmed death receptor 1 (PD-1), T-lymphocyte-associated protein 4 (CTLA-4), and others, has been widely applied in CRC and has achieved encouraging results in some patients and has become a hot topic in both clinical and basic research.

Objective

This study undertakes a comprehensive bibliometric analysis of ICB research in CRC, aiming to evaluate the current status, identify future trends, and provide scientific insights for researchers and decision-makers.

Methods

Utilizing the Web of Science Core Collection (WoSCC), articles focusing on ICB i

SUBMITTER: Chang Y 

PROVIDER: S-EPMC11560439 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature